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1

W07-IS-002 How to raise HDL cholesterol levels?Insight from hereditary disorders of HDL metabolism

Kuivenhoven, J.A., Hovingh, G.K., de Groot, E., Kastelein, J.J.P.

Journal:

Atherosclerosis Supplements

Year:

2005

Language:

english

File:

PDF, 137 KB

english, 2005

2

High-density lipoprotein proteome dynamics in human endotoxemia

Johannes HM Levels, Pierre Geurts, Helen Karlsson, Raphaël Marée, Stefan Ljunggren, Louise Fornander, Louis Wehenkel, Mats Lindahl, Erik SG Stroes, Jan A Kuivenhoven, Joost CM Meijers

Journal:

Proteome Science

Year:

2011

Language:

english

File:

PDF, 1.62 MB

english, 2011

3

Lipoprotein(a) as a cardiovascular risk factor: current status

Nordestgaard, B. G., Chapman, M. J., Ray, K., Boren, J., Andreotti, F., Watts, G. F., Ginsberg, H., Amarenco, P., Catapano, A., Descamps, O. S., Fisher, E., Kovanen, P. T., Kuivenhoven, J. A., Lesnik,

Journal:

European Heart Journal

Year:

2010

Language:

english

File:

PDF, 479 KB

english, 2010

4

High prevalence of mutations in LCAT in patients with low HDL cholesterol levels in the Netherlands: Identification and characterization of eight novel mutations

Adriaan G. Holleboom, Jan A. Kuivenhoven, Frank Peelman, Alinda W. Schimmel, Jorge Peter, Joep C. Defesche, John J.P. Kastelein, G. Kees Hovingh, Erik S. Stroes, Mohammad Mahdi Motazacker

Journal:

Year:

2011

Language:

english

File:

PDF, 337 KB

english, 2011

5

AAV gene therapy as a means to increase apolipoprotein (Apo) A-I and high-density lipoprotein-cholesterol levels: correction of murine ApoA-I deficiency

Stefan F. C. Vaessen, Robert Jan Veldman, Elisabeth M. Comijn, Jolanda Snapper, Jeroen A. Sierts, Karin van den Oever, Stuart G. Beattie, Jaap Twisk, Jan Albert Kuivenhoven

Journal:

The Journal of Gene Medicine

Year:

2009

Language:

english

File:

PDF, 301 KB

english, 2009

6

Physical activity modulates the effect of a lipoprotein lipase mutation (D9N) on plasma lipids and lipoproteins

Jolanda MA Boer, Jan Albert Kuivenhoven, Edith JM Feskens, Evert G Schouten, Louis M Havekes, Jacob C Seidell, John JP Kastelein, Daan Kromhout

Journal:

Clinical Genetics

Year:

1999

Language:

english

File:

PDF, 234 KB

english, 1999

7

HDL deficiency and atherosclerosis: lessons from Tangier disease

G. K. Hovingh, J. A. Kuivenhoven, R. J. Bisoendial, A. K. Groen, M. van Dam, A. van Tol, C. Wellington, M. R. Hayden, A. H. M. Smelt, J. J. P. Kastelein

Journal:

Journal of Internal Medicine

Year:

2004

Language:

english

File:

PDF, 46 KB

english, 2004

8

Reconstituted HDL infusion restores endothelial function in patients with type 2 diabetes mellitus

M. Nieuwdorp, M. Vergeer, R. J. Bisoendial, J. op ‘t Roodt, H. Levels, R. S. Birjmohun, J. A. Kuivenhoven, R. Basser, T. J. Rabelink, J. J. P. Kastelein, E. S. G. Stroes

Journal:

Year:

2008

Language:

english

File:

PDF, 113 KB

english, 2008

9

Cholesteryl ester transfer protein concentration is associated with progression of atherosclerosis and response to pravastatin in men with coronary artery disease (REGRESS)

A. H. E. M. Klerkx, G. J. De Grooth, A. H. Zwinderman, J. W. Jukema, J. A. Kuivenhoven, J. J. P. Kastelein

Journal:

European Journal of Clinical Investigation

Year:

2004

Language:

english

File:

PDF, 134 KB

english, 2004

10

Reduced leucocyte cholesteryl ester transfer protein expression in acute coronary syndromes

D. Ye, A. O. Kraaijeveld, R. W. Grauss, S. M. Willems, L. C. Van Vark-van der Zee, S. C. A. De Jager, M. Jauhiainen, J. A. Kuivenhoven, G. M. Dallinga-Thie, D. E. Atsma, P. C. W. Hogendoorn, E. A. L.

Journal:

Journal of Internal Medicine

Year:

2008

Language:

english

File:

PDF, 923 KB

english, 2008

11

Common variants of multiple genes that control reverse cholesterol transport together explain only a minor part of the variation of HDL cholesterol levels

SM Boekholdt, OW Souverein, MWT Tanck, GK Hovingh, JA Kuivenhoven, RIG Peters, H Jansen, PMH Schiffers, EE Van Der Wall, PA Doevendans, PH Reitsma, AH Zwinderman, JJP Kastelein, JW Jukema

Journal:

Clinical Genetics

Year:

2006

Language:

english

File:

PDF, 153 KB

english, 2006

12

Elevated cholesteryl ester transfer protein concentration is associated with an increased risk for cardiovascular disease in women, but not in men, with Type 2 diabetes: the Hoorn Study

M. Alssema, J. M. Dekker, J. A. Kuivenhoven, G. Nijpels, T. Teerlink, P. G. Scheffer, M. Diamant, C. D. A. Stehouwer, L. M. Bouter, R. J. Heine

Journal:

Diabetic Medicine

Year:

2007

Language:

english

File:

PDF, 168 KB

english, 2007

13

ApoAI-phosphatidylcholine infusion neutralizes the atherothrombotic effects of C-reactive protein in humans

S. I. VAN LEUVEN, R. S. BIRJMOHUN, R. FRANSSEN, R. J. BISOENDIAL, H. DE KORT, J. H. M. LEVELS, R. L. BASSER, J. C. M. MEIJERS, J. A. KUIVENHOVEN, J. J. KASTELEIN, E. S. STROES

Journal:

Journal of Thrombosis and Haemostasis

Year:

2009

Language:

english

File:

PDF, 281 KB

english, 2009

14

Genetic determinants of plasma HDL-cholesterol levels in familial hypercholesterolemia

van Aalst-Cohen, Emily S, Jansen, Angelique C M, Boekholdt, S Matthijs, Tanck, Michael W T, Fontecha, Marcel R, Cheng, Suzanne, Li, Jia, Defesche, Joep C, Kuivenhoven, Jan Albert, Kastelein, John J P

Journal:

European Journal of Human Genetics

Year:

2005

Language:

english

File:

PDF, 93 KB

english, 2005

15

Effectiveness of Inhibition of Cholesteryl Ester Transfer Protein by JTT-705 in Combination With Pravastatin in Type II Dyslipidemia

Jan Albert Kuivenhoven, Greetje J. de Grooth, Hitoshi Kawamura, Anke H. Klerkx, Francois Wilhelm, Mieke D. Trip, John J.P. Kastelein

Journal:

The American Journal of Cardiology

Year:

2005

Language:

english

File:

PDF, 85 KB

english, 2005

16

Fasting cholesteryl ester transfer protein concentration is independently associated with the postprandial decrease in high-density lipoprotein cholesterol concentration after fat-rich meals: the Hoorn prandial study

Marjan Alssema, Karim El-Harchaoui, Roger K. Schindhelm, Michaela Diamant, Giel Nijpels, Piet J. Kostense, Tom Teerlink, Robert J. Heine, Geesje M. Dallinga-Thie, Jan A. Kuivenhoven, Jacqueline M. Dek

Journal:

Year:

2010

Language:

english

File:

PDF, 285 KB

english, 2010

17

Familial high-density-lipoprotein deficiency causing corneal opacities (fish eye disease) in a family of Dutch descent

J. J. P. KASTELEIN, P. H. PRITCHARD, D. W. ERKELENS, J. A. KUIVENHOVEN, J. J. ALBERS, J. J. FROHLICH

Journal:

Journal of Internal Medicine

Year:

1992

Language:

english

File:

PDF, 2.06 MB

english, 1992

18

Mutations in LPL, APOC2, APOA5, GPIHBP1 and LMF1 in patients with severe hypertriglyceridaemia

R. P. Surendran, M. E. Visser, S. Heemelaar, J. Wang, J. Peter, J. C. Defesche, J. A. Kuivenhoven, M. Hosseini, M. Péterfy, J. J. P. Kastelein, C. T. Johansen, R. A. Hegele, E. S. G. Stroes, G. M. Dal

Journal:

Journal of Internal Medicine

Year:

2012

Language:

english

File:

PDF, 307 KB

english, 2012

19

AN APPROACH TOWARD AUTOMATION OF ANTINUCLEAR ANTIBODY (ANA) DETERMINATION

J. H. ten Veen, A. C. J. Kuivenhoven, T. E. W. Feltkamp

Journal:

Annals of the New York Academy of Sciences

Year:

1971

Language:

english

File:

PDF, 1.52 MB

english, 1971

20

Glycerol Treated Human Red Cells Frozen with Liquid Nitrogen

H. W. Krijnen, J. J. Fr. M. de Wit, A. C. J. Kuivenhoven, J. A. Loos, H. K. Prins

Journal:

Year:

1964

Language:

english

File:

PDF, 552 KB

english, 1964

21

High-Density Lipoprotein Attenuates Inflammation and Coagulation Response on Endotoxin Challenge in Humans

Birjmohun, R. S., van Leuven, S. I., Levels, J. H.M., van 't Veer, C., Kuivenhoven, J. A., Meijers, J. C.M., Levi, M., Kastelein, J. J.P., van der Poll, T., Stroes, E. S.G.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2007

Language:

english

File:

PDF, 622 KB

english, 2007

22

Patients with low HDL-cholesterol caused by mutations in LCAT have increased arterial stiffness

van den Bogaard, Bas, Holleboom, Adriaan G., Duivenvoorden, Raphaël, Hutten, Barbara A., Kastelein, John J.P., Hovingh, G. Kees, Kuivenhoven, Jan Albert, Stroes, Erik S.G., van den Born, Bert-Jan H.

Journal:

Atherosclerosis

Year:

2012

Language:

english

File:

PDF, 258 KB

english, 2012

23

AAV1-LPLS447X gene therapy reduces hypertriglyceridemia in apoE2 knock in mice

Jaap Rip, Ko Willems van Dijk, Jeroen A. Sierts, John J.P. Kastelein, Jaap Twisk, Jan Albert Kuivenhoven

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2006

Language:

english

File:

PDF, 256 KB

english, 2006

24

Efficient lowering of triglyceride levels in mice by human apoAV protein variants associated with hypertriglyceridemia

Stefan F.C. Vaessen, Jeroen A. Sierts, Jan Albert Kuivenhoven, Frank G. Schaap

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 283 KB

english, 2009

25

Characterization of antioxidant/anti-inflammatory properties and apoA-I-containing subpopulations of HDL from family subjects with monogenic low HDL disorders

Georgios Daniil, Alexia A.P. Phedonos, Adriaan G. Holleboom, Mohammad Mahdi Motazacker, Letta Argyri, Jan Albert Kuivenhoven, Angeliki Chroni

Journal:

Clinica Chimica Acta

Year:

2011

Language:

english

File:

PDF, 629 KB

english, 2011

26

T→G or T→A mutation introduced in the branchpoint consensus sequence of intron 4 of lecithin:cholesterol acyltransferase (LCAT) gene: intron retention causing LCAT deficiency

Min Li, Jan Albert Kuivenhoven, Amir F Ayyobi, P.Haydn Pritchard

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1998

Language:

english

File:

PDF, 376 KB

english, 1998

27

The preservation of blood cells in the frozen state: Experiences and current methods in the Netherlands

H.W. Krijnen, A.C.J. Kuivenhoven, J.J.F.M. De Wit

Journal:

Year:

1968

Language:

english

File:

PDF, 1.25 MB

english, 1968

28

Microscopic observation of the freezing and thawing of suspensions of erythrocytes

A.C.J. Kuivenhoven

Journal:

Transfusion (Elsevier)

Year:

1966

Language:

english

File:

PDF, 130 KB

english, 1966

29

Intermediate rate freezing of human red cells

H.W. Krijnen, J.J.Fr.M. de Wit, A.C.C. Kuivenhoven

Journal:

Transfusion (Elsevier)

Year:

1966

Language:

english

File:

PDF, 311 KB

english, 1966

30

[14] IN VITRO AND EX VIVO FUNCTIONAL CHARACTERIZATION ON NEWLY IDENTIFIED ATP BINDING CASSETTE A1 MUTATIONS

C. Candini, R. Franssen, A.W. Schimmel, J. Peter, G.M. Dallinga-Thie, G.K. Hovingh, M. Vergeer, A.G. Holleboom, T. Fasano, L. Bocchi, S. Calandra, J.J.P. Kastelein, E.S. Stroes, J.A. Kuivenhoven, M.M.

Journal:

Nutrition, Metabolism and Cardiovascular Diseases

Year:

2009

Language:

english

File:

PDF, 54 KB

english, 2009

31

Fish Eye Disease and LCAT-deficiency, extremes of one phenotype. A novel LCAT-mutation in a large family of Dutch descent

J.A. Kuivenhoven, H. Wiebusch, E. Van Voorst tot Voorst, J.S. Hill, P.H. Pritchard, H. Funke, J.J.P. Kastelein

Journal:

Atherosclerosis

Year:

1994

Language:

english

File:

PDF, 157 KB

english, 1994

32

A patient with Fish Eye Disease (FED): increased risk for CHD?

J.A. Kuivenhoven, P.H. Pritchard, A.F.H. Stalenhoef, J.S. Hill, J.J.P. Kastelein

Journal:

Atherosclerosis

Year:

1994

Language:

english

File:

PDF, 157 KB

english, 1994

33

The importance of intron sequence: an LCAT-intron base substitution resulting in a null allele

J.A. Kuivenhoven, H. Wiebusch, P.H. Pritchard, J.S. Hill, H. Funke, J.J.P. Kastelein

Journal:

Atherosclerosis

Year:

1994

Language:

english

File:

PDF, 157 KB

english, 1994

34

Carotid endothelial shear stress assessed by 3T-MRI is associated with aortic pulse wave velocity in healthy volunteers

R. Duivenvoorden, B. van den Boogaard, A.G. Holleboom, A.J. Nederveen, J.S. Lameris, J.J.P. Kastelein, J.A. Kuivenhoven, E.S.G. Stroes, E. de Groot

Journal:

Artery Research

Year:

2010

Language:

english

File:

PDF, 104 KB

english, 2010

35

Heterozygosity for ABCA1 gene mutations: effects on enzymes, apolipoproteins and lipoprotein particle size

J.A. Kuivenhoven, G.K. Hovingh, A. van Tol, M. Jauhiainen, C. Ehnholm, J.C. Fruchart, E.A. Brinton, J.D. Otvos, A.H.M. Smelt, A. Brownlee, A.H. Zwinderman, M.R. Hayden, J.J.P. Kastelein

Journal:

Atherosclerosis

Year:

2003

Language:

english

File:

PDF, 102 KB

english, 2003

36

The relationship between cholesteryl ester transfer protein levels and risk factor profile in patients with familial hypercholesterolemia

Greetje J de Grooth, Tineke J Smilde, Sanne van Wissen, Anke H.E.M Klerkx, Aeilko H Zwinderman, Jean-Charles Fruchart, John J.P Kastelein, Anton F.H Stalenhoef, Jan Albert Kuivenhoven

Journal:

Atherosclerosis

Year:

2004

Language:

english

File:

PDF, 114 KB

english, 2004

37

Enhanced apoB48 metabolism in lipoprotein lipase X447 homozygotes

Melchior C. Nierman, Jaap Rip, Jan Albert Kuivenhoven, Naohiko Sakai, John J.P. Kastelein, Monique G.M. de Sain-van der Velden, Erik S.G. Stroes, Berthil H.C.M.T. Prinsen

Journal:

Atherosclerosis

Year:

2007

Language:

english

File:

PDF, 165 KB

english, 2007

38

Adeno-associated virus LPLS447X gene therapy in LDL receptor knockout mice

Jaap Rip, Jeroen A. Sierts, Stefan F.C. Vaessen, John J.P. Kastelein, Jaap Twisk, Jan Albert Kuivenhoven

Journal:

Atherosclerosis

Year:

2007

Language:

english

File:

PDF, 289 KB

english, 2007

39

High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants

Bernadette A.C. van Acker, Gert-Jan Botma, Aeilko H. Zwinderman, Jan Albert Kuivenhoven, Geesje M. Dallinga-Thie, Eric J.G. Sijbrands, Jolanda M.A. Boer, Jacob C. Seidell, J. Wouter Jukema, John J.P.

Journal:

Atherosclerosis

Year:

2008

Language:

english

File:

PDF, 170 KB

english, 2008

40

Reduced fecal sterol excretion in subjects with familial hypoalphalipoproteinemia

Karim El Harchaoui, Remco Franssen, G. Kees Hovingh, Radjesh J. Bisoendial, Frans Stellaard, Folkert Kuipers, John J.P. Kastelein, Jan Albert Kuivenhoven, Erik S.G. Stroes, Albert K. Groen

Journal:

Atherosclerosis

Year:

2009

Language:

english

File:

PDF, 170 KB

english, 2009

41

CO-SEGREGATION OF EL AND HL VARIANTS WITH HIGH PLASMA HDL-C LEVELS IN FAMILIES WITH HYPERALPHALIPOPROTAEINEMIA

M.M. Motazacker, A.G. Holleboom, R. Franssen, J. Azevedo, G.K. Hovingh, J.J.P. Kastelein, J.A. Kuivenhoven

Journal:

Atherosclerosis

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

42

Identification and characterization of novel loss of function mutations in ATP-binding cassette transporter A1 in patients with low plasma high-density lipoprotein cholesterol

C. Candini, A.W. Schimmel, J. Peter, A.E. Bochem, A.G. Holleboom, M. Vergeer, R.P.F. Dullaart, G.M. Dallinga-Thie, G.K. Hovingh, K.L. Khoo, T. Fasano, L. Bocchi, S. Calandra, J.A. Kuivenhoven, M.M. Mo

Journal:

Atherosclerosis

Year:

2010

Language:

english

File:

PDF, 377 KB

english, 2010

43

Plasma levels of 27-hydroxycholesterol in humans and mice with monogenic disturbances of high density lipoprotein metabolism

Ratna Karuna, Adriaan G. Holleboom, Mohammad M. Motazacker, Jan Albert Kuivenhoven, Ruth Frikke-Schmidt, Anne Tybjaerg-Hansen, Spiros Georgopoulos, Miranda van Eck, Theo J.C. van Berkel, Arnold von Ec

Journal:

Atherosclerosis

Year:

2011

Language:

english

File:

PDF, 226 KB

english, 2011

44

Proteinuria in early childhood due to familial LCAT deficiency caused by loss of a disulfide bond in lecithin:cholesterol acyl transferase

A.G. Holleboom, J.A. Kuivenhoven, C.C. van Olden, J. Peter, A.W. Schimmel, J.H. Levels, R.M. Valentijn, P. Vos, J.C. Defesche, J.J.P. Kastelein, G.K. Hovingh, E.S.G. Stroes, C.E.M. Hollak

Journal:

Atherosclerosis

Year:

2011

Language:

english

File:

PDF, 371 KB

english, 2011

45

Plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolism

Ratna Karuna, Rebekka Park, Alaa Othman, Adriaan G. Holleboom, Mohammad Mahdi Motazacker, Iryna Sutter, Jan Albert Kuivenhoven, Lucia Rohrer, Hugues Matile, Thorsten Hornemann, Markus Stoffel, Kathari

Journal:

Atherosclerosis

Year:

2011

Language:

english

File:

PDF, 555 KB

english, 2011

46

Lecithin: Cholesterol Acyltransferase (LCAT) is required for normal brain apoE metabolism in mice

Veronica Hirsch-Reinshagen, James Donkin, Sophie Stukas, Jianjia Fan, John S. Parks, Jan Albert Kuivenhoven, Dieter Lütjohann, Haydn Pritchard, Cheryl L. Wellington

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 45 KB

english, 2009

47

IP-0038 A novel apoA-I mutation (Leu178Pro), identified by whole genome linkage approach, predisposes to endothelial dysfunction, increased arterial wall thickness and premature coronary artery disese

Hovingh, G.K., Bisoendial, R.J., Brownlie, A., Samuels, M., Kuivenhoven, J.A., De Groot, E., Stroes, E.S.G., Hayden, M.R., Kastelein, J.J.P.

Journal:

Atherosclerosis Supplements

Year:

2003

Language:

english

File:

PDF, 63 KB

english, 2003

48

Mo-W7:5 Myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals

Meuwese, M.C., Boekholdt, S.M., Kastelein, J.J.P., Hazen, S.L., Kuivenhoven, J.A., Bingham, S.A., Wareham, N.J., Schaub, R., Stroes, E.S.G., Thaw, K.T.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 147 KB

english, 2006

49

Mo-W5:2 A gene therapy approach to treat human lipoprotein lipase deficiency

Nierman, M.C., Stroes, E.S., Twisk, J., Rip, J., Dijkhuizen, P., Ross, C.J.D., Bakker, A.C., Hermens, W.T., Meulenberg, J.M., Hayden, M.R., Kastelein, J.J.P., Kuivenhoven, J.A.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 157 KB

english, 2006

50

Mo-P1:109 LDL particle number and risk for future cardiovascular risk

Elharchaoui, K., Van Der Steeg, W.A., Boekholdt, S.M., Stroes, E.S.G., Otvos, J.D., Kuivenhoven, J.A., Bingham, S.A., Day, N.E., Khaw, K.T., Kastelein, J.J.P.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 150 KB

english, 2006

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